In-cell distance determination by EPR reveals essential structural information about biomacromolecules under native conditions. For the first time, the pulsed EPR technique RIDME (relaxation induced dipolar modulation enhancement) was utilized for distance measurements inside cells. It provides a five-times improved sensitivity as compared to the previously used double electron-electron resonance approach. Copyright: Research group Professor Malte Drescher, University of Konstanz

New technique for in-cell distance determination

Researchers from the University of Konstanz, Bielefeld University and ETH Zurich demonstrate for the first time that the pulsed EPR technique RIDME (relaxation-induced dipolar modulation enhancement) can be used for in-cell distance determination in biomacromolecules. Applied within the cell, RIDME improves significantly on conventional double electron–electron resonance (DEER) measurements.

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Luftaufnahme vom Konstanzer Trichter

Die Auswirkungen Künstlicher Intelligenz

Ein Studierendenteam der Universität und Hochschule Konstanz sowie der Musikhochschule Trossingen wurde von der Initiative „Wissenschaft im Dialog“ für ihr Konzept zu Künstlicher Intelligenz ausgezeichnet

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David Schleheck, Anna Burrichter and Karin Denger. This picture does not show the collaboration partners from Harvard University Emily Balskus, Spencer Peck and Stephania Irwin. Photo: University of Konstanz

Enzyme discovered

At the University of Konstanz, in cooperation with Harvard University, a key enzyme for formation of harmful hydrogen sulphide in the human gut by Bilophila bacteria has been discovered.

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